| Product name: YDL223C |
| Other Name: HBT1 |
| Appearance:Yellowish Powder |
| CAS:489408-02-8 |
| M.F.:C16H17F3N4O2S |
| M.W.:386.39 |
| Specification:99% |
Benefits of HBT1
AMPA-R agonists, which can activate all AMPA-Rs, including resting receptors, have been shown to induce both desensitization of AMPA-R and seizure (Yamada, 1998; Beattie et al., 2000; Ehlers, 2000). AMPA-R potentiators are considered to have better pharmacological profiles because of their selective enhancement of physiologic activation of AMPA-Rs in the brain. However, AMPA-R potentiators such as LY451646, LY451395, and S18986 are reported to elicit bell-shaped responses in various pharmacological effects: LY451646 is reported to show bell-shaped responses in in vivo BDNF induction, and the bell-shaped response of LY451395 in the radial maze task was described in the introduction section of a report about LY451395 (Mackowiak et al., 2002; Bai et al., 2003; Fowler et al., 2004; Jhee et al., 2006; Bernard et al., 2010). PF-4778574 is reported to have less than a 30-fold safety margin against seizure in rodents (Shaffer et al., 2013). Thus, discovery of AMPA-R potentiators with lower risks of these issues is needed.
Shipping Advise:
1. By Express Suitable for under 50kg, Fast:3-7 days.
Door to door service. Easy to pick up the goods.
2. By Air Suitable for more than 50 kg, Fast:3-7 days,
Airport to airport. professional broker needed.
3. By sea Suitable for more than 500kg. Slow: 5-45 days,
Low cost. Port to Port, professional broker needed.
Service:
1. Any inquiries will be replied within 24 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantage:
High quality-- High-concentration products, strictly control the quality
Low price--Reasonable and flexible price matched with high quality
Samll quantity--Free sample for your evaluation
Professional team--Professional and experienced researchers develop products
Timely delivery--Promptly delivery by well-reputed shipping lines
Faster delivery--Sample order in stock and 3-7 days for bulk production.
We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
After Sales Service
--24 Hours online service for your consult.
--Help choose the right model, and a series of services, person, and advice.
--Give you the best offer.
--Provide discount for many sets order.
--Do customer's request.
--Choose payment term you convenient.
--Promptly production and delivery, inform you in time.
--Can provide invoice value as you like to decrease your tax.
1.Will you supply samples for test the quality?
We'd like to offer the samples for the quality evaluation,the shipping cost is borne by customers.
2.What is the payment term?
T/T, Western Union or L/C and so on.
3.What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing
Liquid: glass bottle or PTFE bottle for inner packing
Bulk order: Fiber drum or steel drum.
4.What is your delivery term and delivery period?
FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you.
The sample within 5 days, and bulk order within 7 days.
5.How to delivery by express?
A: Parcel will be shipped out in 3 working days after payment. Usually we use EMS, ePacket, Fedex, DHL, TNT and USA Domestic mixed shipping and so on.
6.Is there a discount?
A: Yes, for larger quantity, we always support with better price.
7.What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
8.How to make orders?
A: Send inquiry to us,we do the offer. Payment via Western Union, Moneygram, Bank Account ect.. Then we will arrange shipping. After delivery we will offer tracking No...
9. Why I can not find the product I require in this shop?
A: You can contact with us,We supply comprehensive and series chemical intermediates and some other scientific & healthy materials, we didn't upload all our list on this site.
Audited Supplier 
){kind=link}